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New Roots Herbal D-Mannose and Cranberry is formulated as an effective alternative to antibiotics for the treatment of often-recurring urinary tract infections (UTIs). D-Mannose and Cranberry is formulated with therapeutic proportions of three proven natural ingredients. D-Mannose is a simple naturally-occurring sugar that is not converted to glycogen in the liver; it enters the blood stream directly, and upon exposure within the kidney, it attaches to Escherichia coli bacteria for harmless excretion. The effectiveness of D-Mannose and Cranberry is reflected by the fact that approximately eighty percent of UTIs result from infections caused by E. coli.